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KMID : 1040620200260040633
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Clinical and Molecular Hepatology
2020 Volume.26 No. 4 p.633 ~ p.638
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The lymphatic system in alcohol-associated liver disease
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Kondo Reiichiro
Iwakiri Yasuko
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Abstract
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The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.
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KEYWORD
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Lymphangiogenesis, Vascular endothelial growth factor C, Inflammation, Lymphatics
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